Against Mono Red Madness, Pyroblast is dead weight against their red cards and should stay home; against your own errant instincts, resist boarding it in, but Blue Elemental Blast is fully live to counter their red spells and destroy their red permanents. Also lean on your existing Skred and Fiery Cannonade to clear Guttersnipe and Voldaren Epicure, while using Skred to take down Kessig Flamebreather. Spell Pierce is weak since their spells are cheap and they play around it easily, and Murmuring Mystic's 1/5 body is fine on defense but you need more interaction than tokens against a fast burn plan, so trim one copy. Prioritize surviving to Tolarian Terror and Skred while using Counterspell on their key payoff creatures.

Dimir Control's clock relies partly on graveyard-fueled threats like Gurmag Angler (delve) and Ninja of the Deep Hours triggers, and Tormod's Crypt can strip their graveyard to blunt Gurmag Angler's delve cost, though note it does nothing against their Spellstutter Sprite or hand-based plays. Annul is mostly a sideboard hedge against their few nonland artifacts (Contaminated Aquifer isn't an artifact, so Annul has limited targets here) — consider this a lower-impact include, but their deck runs almost no artifacts or enchantments, so weigh cutting Annul back if you find better options; still, it's a reasonable speculative slot. Fiery Cannonade has few good targets against their small creature suite of 1-3 toughness fliers like Spellstutter Sprite and Faerie Seer, so trimming it slightly for grindier tools is reasonable. This is a long, grindy control mirror where card advantage engines like Lorien Revealed and Murmuring Mystic are premium — protect them with Counterspell.

Affinity is a creature swarm deck (Refurbished Familiar, Utrom Monitor, Kor Skyfisher, Glint Hawk) that also leans on artifacts like Cryogen Relic and Blood Fountain for card advantage, making Annul strong against their key artifact spells. Cast into the Fire's artifact-exile mode can remove a problematic Cryogen Relic or Blood Fountain, while its damage mode cleans up 1-toughness creatures like Baleful Strix and Refurbished Familiar. Spell Pierce is weak since affinity's costs are frequently reduced to nothing, letting them pay through the tax easily, so trim it along with Preordain for these proactive answers. Fiery Cannonade remains excellent against their small creatures and should stay in at full count.