Rakdos Reanimator is your best matchup in the format: Leyline of the Void in the opening hand is a complete lockout, exiling every creature they attempt to put into the graveyard and rendering their entire engine — Faithless Looting, Reanimate, Animate Dead, Shallow Grave — utterly useless. Even without Leyline, Trinisphere on turn one collapses their ritual-based economy by making Dark Ritual, Lotus Petal, and Unmask all cost three, preventing the explosive turn-one or turn-two reanimation. Thoughtseize is their main interaction with your prison pieces, so deploying your lock element on the very first turn before they can sculpt their hand is essential — do not wait for a perfect setup. Ensnaring Bridge handles the rare case where a massive threat resolves and gives you time to Karn for a more permanent answer. Karn can also wish for Tormod's Crypt mid-game as a second graveyard hate piece if Leyline is not in hand, ensuring you never run out of answers.