Ruby Storm wants to chain rituals and cantrips (Desperate Ritual, Pyretic Ritual, Manamorphose, Wrenn's Resolve) into a Grapeshot or Past in Flames kill, and Mystical Dispute is a full-price but still solid 3-mana counter here (their spells are red, so its discount never applies) that stops a key ritual, Ral, Monsoon Mage, or Past in Flames from resolving and buys crucial time. We trim Quantum Riddler since its 5-mana investment is too slow against a combo deck that can kill out of nowhere, and tapping out for it is dangerous. Force of Negation and Subtlety remain essential as free interaction on their turn to disrupt their combo turn without using our own mana. Prioritize proactive pressure with Crashing Footfalls and Violent Outburst to force them to find a kill before we close the game.