Affinity is almost entirely artifacts and enchantments, so Force of Vigor is devastating — it can two-for-one their Weapons Manufacturing, Mox Opal, Pinnacle Emissary, or Engineered Explosives, unraveling their whole manabase and threat base at once. Chalice of the Void set to X=0 counters spells with mana value 0 like Mishra's Bauble, Mox Opal, Welding Jar, and Claws of Gix, crippling their ability to function, though it affects both players if a spell with matching mana value is cast. This matchup is a race against a very low curve, so trim the slowest top-end (Ulamog, extra Emrakul copies, Drowner of Truth) for maximum proactive disruption.