Dimir Midrange is full of cheap cantrips and interaction (Preordain, Fatal Push, Counterspell, Thoughtseize), so Magebane Lizard punishes them for developing their hand and can rack up damage quickly on turns where they try to both interact and draw cards. Blood Moon disrupts their five-color-adjacent manabase built on fetches and dual lands like Watery Grave and Undercity Sewers, potentially locking them off black or blue mana entirely. Board out Hobgoblin and Flameblade Adept, which die easily to Fatal Push and Orcish Bowmasters triggers and don't pressure a deck with efficient removal. Keep your discard outlets and hasty threats coming to play around their countermagic (Counterspell, Force of Negation, Spell Snare) by presenting multiple threats per turn.