Esper Control is loaded with countermagic (Counterspell, Orim's Chant, Spell Snare) and sweepers (Wrath of the Skies, Supreme Verdict), so Force of Negation lets you fight through their counterspell suite for free or protect your own key spell, while Mystical Dispute is a cheap answer to their Teferi, Time Raveler or Teferi, Hero of Dominaria that can lock you out of countermagic and card advantage. Metallic Rebuke is weak here since they run very few cheap artifacts, so it's trimmed for proactive disruption. Play around Wrath of the Skies by not overcommitting, and use Urza's Saga plus Cori-Steel Cutter to generate resilient, sweeper-resistant threats. Prioritize countering their planeswalkers and sweepers over their card draw when choices arise.