Force of Vigor destroys the Blade of the Bloodchief that powers their Basking Broodscale combo loop, and can be cast for free by exiling a green card to disrupt them on their turn before the loop goes off. It can also destroy Urza's Saga, since it is an Enchantment Land, which cuts into their mana engine, but it cannot touch Eldrazi Temple, which is a plain land. Brotherhood's End and Force of Vigor are both cascade-safe: Shardless Agent and Violent Outburst only hit cards with mana value below 3, and Brotherhood's End is mana value 3 while Force of Vigor is mana value 4. Brotherhood's End can wipe their Eldrazi Spawn tokens and small Glaring Fleshraker before the combo goes online, or destroy a resolved Blade and other cheap artifacts outright with its artifact-destruction mode. Keep Endurance in as a flash, reach 3/4 body, and its trigger can put the cards Malevolent Rumble milled into their graveyard on the bottom of their library. Trim cards that are slow or low-impact here, since this matchup is about disrupting their specific combo pieces before they go off.