Domain Zoo is an aggressive creature deck built around Wild Nacatl, Territorial Kavu, and Ragavan, so Toxic Deluge is an excellent sweeper that resets their board cheaply while your own Emperor of Bones and Nethergoyf survive at low X values. Dismember is efficient removal for a 2-life cost against their early aggressive creatures when you need to stay on curve. Inquisition of Kozilek is serviceable but less impactful than sweeping their board, and Thought-Knot Seer is a worse rate here since you want to be interacting rather than tapping out against a deck that curves out with one-mana threats and burn. Keep Fatal Push, Thoughtseize, and Kozilek's Command as efficient, flexible answers to their low-toughness creatures.