This matchup is a race against Urza's Saga, Eldrazi Temple, and Ugin's Labyrinth ramping into Emrakul and Devourer of Destiny; Damping Sphere blunts the multi-mana lands and slows Kozilek's Command/Malevolent Rumble value chains. Surgical Extraction can strip a key Urza's Saga or Basking Broodscale copy after it hits the graveyard, and the second Force of Despair is excellent against their many enters-the-battlefield ramp/value creatures cast in a single turn. Dauthi Voidwalker is weak here since it dies to Kozilek's Command exile, cannot block their Blade of the Bloodchief-fueled attackers due to shadow, and doesn't pressure their colorless-heavy plan, while Soul Spike is too slow against a deck assembling lethal Emrakul turns. Keep Fatal Push, Thoughtseize, and Inquisition of Kozilek maximized to strip their engine pieces before they land.