Neobrand aims to chain Summoner's Pact into Eldritch Evolution or Neoform, ultimately cheating Griselbrand, Atraxa, Grand Unifier, or Ghalta, Stampede Tyrant into play, so disrupting their combo sequence is the priority. Damping Sphere taxes their multi-spell combo turns by increasing the cost of each subsequent spell cast, while Force of Despair punishes them for cheating a fresh creature into play the same turn it enters. Surgical Extraction can strip a critical Neoform after they cast one, denying the redundant copy. Cut the two Inquisition of Kozilek since this combo deck often assembles its plan from tutors rather than raw hand card count, and trim Shadowspear plus a basic land for the added disruption; prioritize Thoughtseize on their key combo pieces before they can chain into a payoff target.