Living End wants to discard its whole hand via cycling and cascade into Living End to reanimate a graveyard full of creatures simultaneously, so graveyard hate and disruption of their cascade spells are the priority. Extra Inquisition of Kozilek can strip a key enabler like Violent Outburst or Shardless Agent before they set up. Surgical Extraction is at its best here, letting us exile all copies of Living End from hand/graveyard/library once we see one, which can functionally blank their whole plan. Ashiok, Dream Render lets us proactively exile their graveyard on our turn to strip their reanimation targets; March of Wretched Sorrow and Fell the Profane are cut since Force of Despair already covers the 'kill everything that entered this turn' angle against their mass reanimation.