Esper Ephemerate leans on value creatures like Baleful Strix, Mulldrifter, and Archaeomancer, often blinking them with Ephemerate for repeated ETB value, so graveyard hate isn't the main plan here, but Relic of Progenitus gives you a cheap way to cut off Archaeomancer recursion and replaces itself with a card when you crack it. Keep Suffocating Fumes in: its -1/-1 kills Baleful Strix and Refurbished Familiar outright, though Murmuring Mystic (a 1/5) will survive it. Cut Debt to the Kami, since your opponent chooses which creature to exile and can give up the least valuable one in a grindy matchup like this. Keep Counterspell and Agony Warp to answer their Baleful Strix and Refurbished Familiar before Ephemerate re-triggers their enters-the-battlefield value. This is a long, grindy game where card advantage engines like Lorien Revealed and your Ninjutsu creatures should close it out.