Mono-Red Madness is a race where their madness engine — Faithless Looting into Fiery Temper with Kessig Flamebreather and Guttersnipe on board — can kill you out of nowhere, so your priority is keeping the board clear and staying above burn range. Skred is your best card here, cleanly answering Guttersnipe and Kessig Flamebreather before they snowball; use Ephemerate to rebuy Augur of Bolas for card selection early. Hydroblast comes in as premier interaction — it counters Fiery Temper, Lava Dart, Lightning Bolt, and any burn pointed at your face. Breath Weapon sweeps the token and Voldaren Epicure board states without requiring individual answers. Cut Dispel (they have few instants worth countering), Bonder's Ornament and Late to Dinner (too slow), and Ride's End (bounce is poor when they have so many cheap threats to replay).