Orzhov Control plays few creatures worth killing outright but has a lot of impactful noncreature spells and planeswalkers, so proactive counters outperform removal. Disdainful Stroke stops The Wandering Emperor and Elspeth, Storm Slayer (both at mana value 4+). Mystical Dispute catches their blue-adjacent cards only situationally here, but at full price it is still a serviceable catch-all counter against Caretaker's Talent or The Queen of Dale's card advantage engine; keep this in mind if their list skews lower-impact than expected. Lightning Axe's discard cost is a real cost against a deck full of Thoughtseize, so trim it for the extra counterspells.