Enchantress wants to chain enchantment casts for card advantage and ramp through Serra's Sanctum, so Meddling Mage naming Enchantress's Presence, Argothian Enchantress, or Solitary Confinement can completely shut off their engine. Arcane Laboratory limits them to one spell per turn, crippling the chain-casting that fuels their draw engine and mana. Standstill is bad here since they're happy to keep passing while assembling their lock, and Mana Leak is weak since Serra's Sanctum generates excess mana. Keep Disenchant and Annul in for their key enchantments like Opalescence, Solitary Confinement, and Serra's Sanctum-enabling pieces.