Iggy Pop is a creatureless storm combo deck, making all your creature removal completely dead — Smother and Snuff Out come out entirely. Your hand disruption suite of Duress and Cabal Therapy is the backbone of this matchup; prioritize naming Lion's Eye Diamond, Ill-Gotten Gains, and Infernal Contract to dismantle their engine. Powder Keg is exceptional here: activated immediately with zero fuse counters, it simultaneously destroys Lion's Eye Diamond and Lotus Petal, stripping the free mana that makes their storm kills possible. Tormod's Crypt comes in to disrupt the Ill-Gotten Gains loop — hold it and crack it in response to Ill-Gotten Gains to exile their graveyard, preventing them from rebuy their key pieces and breaking the recursion. Withered Wretch in the main can also chip away at their graveyard over multiple activations if the game goes long.