Naturalize is a key answer to Opalescence and Parallax Wave, the core lock pieces of their Replenish plan, letting you destroy the engine before it takes over the game. Tormod's Crypt exiles their graveyard to strip away the enchantments they intend to Replenish back, disrupting their entire reanimation plan proactively. Wall of Roots and two Quirion Rangers come out since this matchup rewards proactive disruption and speed over incremental mana or untapping tricks. Try to apply pressure with Survival of the Fittest threats while holding Naturalize for their key enchantment plays.