Sylvan Safekeeper protects a key creature like Hermit Druid from Smother, since Smother targets and Safekeeper's shroud makes it an illegal target. It does nothing against Chainer's Edict or Pernicious Deed, which don't target the creature, so treat it as insurance against targeted removal only. Extra Cabal Therapy copies help win the discard war and can strip their Duress or Cabal Therapy before it hits you, or take a key threat like Ravenous Baloth. Duress is cut for the more flexible Cabal Therapy package since Duress can't take creatures and The Rock's threats develop over multiple turns, while Cabal Therapy can hit them and be flashed back for repeated disruption. Krosan Reclamation is a low-priority cut since shuffling graveyard cards back into the library does little in a matchup that rewards proactive plays.