Simic Rhythm (41% win rate) is a difficult matchup because their Nature's Rhythm ramp, Spider Manifestation for wide boards, and Craterhoof Behemoth trump your midrange creature plan. Annul disrupts their Nature's Rhythm enchantment and key enablers. Duress strips Craterhoof Behemoth and key burst spells before they can deploy them. Disdainful Stroke counters their expensive threats on the stack. Your Kaito, Bane of Nightmares and Floodpits Drowner apply meaningful pressure that forces them to tap out. Flitterwing Nuisance and Phantom Interference are too marginal, Spell Snare has limited targets, and Soulstone Sanctuary as a utility land is cut for more spell-based disruption to improve your unfavorable game plan.