Temur Lessons plays very few creatures (Questing Druid and Thor are the only ones), making Deadly Cover-Up mostly a blank — trim it for proactive disruption instead. Negate stops their key noncreature spells like Abandon Attachments or It'll Quench Ya!, protecting your own plays from being countered or answered. The extra Duress strips a counterspell or Lesson before it lands, and Ancient Vendetta can strip up to four copies of Tablet of Discovery or Thor from their deck to cut their most impactful card. Keep your maindeck removal for Thor, since it's their only real threat that needs to be answered on the battlefield or in combat.