Leyline of the Void can be started in play from the opening hand, immediately shutting off their graveyard-based plans like Gaea's Will, Echo of Eons flashback, and Runehorn Hellkite's graveyard ability, since their cards are exiled instead of going to the graveyard. It does not stop Beseech the Mirror's bargain or Burning Wish, which don't rely on the graveyard (bargain sacrifices an artifact, enchantment, or token, and Burning Wish exiles itself and fetches a sorcery from outside the game). Disruptor Flute comes out since it is too slow and narrow (naming only one card) against a deck with many different combo pieces like Lion's Eye Diamond, Dark Ritual, and Tendrils of Agony. Keep Thalia, Guardian of Thraben in as one of our best disruptive pieces, taxing every noncreature spell in their deck including Dark Ritual and Gamble.