Devoted Combo wants to assemble Devoted Druid plus Vizier of Remedies or Agatha's Soul Cauldron engines, and while Meltdown only hits artifacts (it does not touch their core creature engine), it can answer Agatha's Soul Cauldron before it turns their board into a counter-synergy threat. Spell Pierce taxes their combo pieces like Green Sun's Zenith or Nature's Rhythm on key turns when they're tapped out. This matchup is primarily a race, so most of our plan stays the same; Violent Urge and one Mutagenic Growth come out since they rarely need to be used defensively against a deck with few early blockers, making room for proactive disruption. Keep pressuring with the full creature and burn suite, since this deck has little reach once they stabilize with Craterhoof Behemoth or Ouroboroid.