Against Mono Red Madness, Pyroblast is dead weight against their red cards and should stay home; against your own errant instincts, resist boarding it in, but Blue Elemental Blast is fully live to counter their red spells and destroy their red permanents. Also lean on your existing Skred and Fiery Cannonade to clear Guttersnipe and Voldaren Epicure, while using Skred to take down Kessig Flamebreather. Spell Pierce is weak since their spells are cheap and they play around it easily, and Murmuring Mystic's 1/5 body is fine on defense but you need more interaction than tokens against a fast burn plan, so trim one copy. Prioritize surviving to Tolarian Terror and Skred while using Counterspell on their key payoff creatures.